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Louis Denis Selected Research

gusacitinib

1/2023Oral spleen tyrosine kinase/Janus Kinase inhibitor gusacitinib for the treatment of chronic hand eczema: Results of a randomized phase 2 study.
10/2019Oral Janus kinase/SYK inhibition (ASN002) suppresses inflammation and improves epidermal barrier markers in patients with atopic dermatitis.

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Louis Denis Research Topics

Disease

7Neoplasms (Cancer)
01/2021 - 11/2002
5Prostatic Neoplasms (Prostate Cancer)
11/2018 - 10/2009
2Colorectal Neoplasms (Colorectal Cancer)
08/2006 - 08/2004
1Eczema
01/2023
1Adenocarcinoma of Lung
05/2022
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
05/2022
1Melanoma (Melanoma, Malignant)
01/2021
1Inflammation (Inflammations)
10/2019
1Pruritus (Itching)
10/2019
1Atopic Dermatitis (Atopic Eczema)
10/2019
1Asthenia
02/2007
1Diarrhea
02/2007
1Embolism (Embolus)
02/2007
1Exanthema (Rash)
02/2007
1Hyperbilirubinemia
02/2007
1Cardiomyopathies (Cardiomyopathy)
02/2007
1Nausea
02/2007
1Thrombocytopenia (Thrombopenia)
02/2007
1Multiple Myeloma
12/2004
1Hematologic Neoplasms (Hematological Malignancy)
12/2004
1Osteosarcoma (Osteogenic Sarcoma)
01/2003
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
01/2003
1Adenocarcinoma
01/2003
1Carcinoma (Carcinomatosis)
11/2002

Drug/Important Bio-Agent (IBA)

4Prostate-Specific Antigen (Semenogelase)IBA
02/2018 - 11/2002
3Irinotecan (Camptosar)FDA LinkGeneric
08/2006 - 08/2004
2gusacitinibIBA
01/2023 - 10/2019
2Topoisomerase I InhibitorsIBA
08/2006 - 12/2004
1Syk KinaseIBA
01/2023
1Janus Kinase InhibitorsIBA
01/2023
1defactinibIBA
05/2022
1Codon (Codons)IBA
05/2022
1Immune Checkpoint InhibitorsIBA
05/2022
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
01/2021
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2021
1ASN007IBA
01/2021
1Janus KinasesIBA
10/2019
1Biomarkers (Surrogate Marker)IBA
10/2019
1Androgen Receptors (Androgen Receptor)IBA
11/2018
1Androgen Antagonists (Antiandrogens)IBA
11/2018
1enzalutamideIBA
11/2018
1cabazitaxelFDA Link
04/2011
1Testosterone (Sustanon)FDA Link
04/2011
1Tyrosine Kinase InhibitorsIBA
02/2007
1Alanine Transaminase (SGPT)IBA
02/2007
1Transaminases (Aminotransferases)IBA
02/2007
12- methoxy- N- (3- (4- ((3- methyl- 4- ((6- methyl- 3- pyridinyl)oxy)phenyl)amino)- 6- quinazolinyl)- 2- propenyl)acetamideIBA
02/2007
1PowdersIBA
08/2006
1Capsules (Microcapsules)IBA
08/2006
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
12/2004
1Phosphotransferases (Kinase)IBA
12/2004
1Type I DNA Topoisomerases (Topoisomerase I)IBA
12/2004
1CaspasesIBA
12/2004
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
01/2003
1PlatinumIBA
01/2003
1CamptothecinIBA
01/2003
1Etoposide (VP 16)FDA LinkGeneric
01/2003

Therapy/Procedure

2Castration
11/2018 - 04/2011
2Therapeutics
12/2004 - 11/2002
1Drug Therapy (Chemotherapy)
05/2022